Effects of Active Principles from S. Miltiorrhiza on Human Endothelial Cells and Platelets
نویسندگان
چکیده
Angiogenesis is a multi-factorial process involving endothelial cells, pericytes, macrophages, angiogenic factors and inhibitors. It plays a fundamental role in many physiological and pathological processes such as wound healing and atherosclerosis. Haemostasis is the arrest of blood loss from damaged blood vessels involving platelet adhesion, activation and blood coagulation. Recent studies suggest these two processes are closely related, because some proteins derived from platelets or the coagulation cascade are involved in controlling angiogenesis (Carmeliet, 2003; Shi et al., 2005).
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